Travasol - Consumer Medicine Information
|Class:||Intravenous nutritional products|
|Form:||Liquid solution, Intravenous (IV)|
|Ingredients:||L alanine, L-arginine, Glycine, L-histidine, L-isoleucine, L leucine, L lysine hydrochloride, L-methionine, L-phenylalanine, L-proline, L-Se, L-threonine, L tryptophan, L-tyrosine, L-valine, Electrolytes, , Sodium chloride , Sodium acetate trihydrate, Dibasic potassium phosphate, Magnesium chloride, hexahydrate, glacial acetic acid (for pH adjustment), nitrogen, water for injection|
Amino acids WITH electrolytes injection 10% w/v
TRAVASOL (Blend B)
Amino acid injection 10% w/v
TRAVASOL (Blend C)
Amino acid injection 10% w/v
About this Medication
What the medication is used for
TRAVASOL E (amino acids WITH electrolytes injection) and TRAVASOL (amino acids injection) are intravenous nutritive supplements used to provide nutrition through a tube into a vein when normal feeding by mouth is not possible or suitable.
TRAVASOL E / TRAVASOL product must only be used under medical supervision.
What it does
The use of TRAVASOL E / TRAVASOL product is a way to ensure that patients who are unable to eat get an adequate intake of energy, nitrogen and other nutrients, and helps to treat or prevent malnutrition.
When it should not be used
TRAVASOL E and TRAVASOL products should not be used if:
- You are allergic to any ingredients (See What the medicinal ingredients are and What the nonmedicinal ingredients are).
- Your body has problems processing certain amino acids and these amino acids are included in TRAVASOL E / TRAVASOL product.
- You have liver failure or coma resulting from liver failure.
Also, TRAVASOL E product should not be used if:
- You have a disorder resulting in high blood levels of substances such as potassium (hyperkalemia), calcium ( hypercalcemia), phosphorus (hyperphosphatemia), sodium (hypernatremia) and magnesium (hypermagnesemia).
- You are receiving calcium-containing intravenous solutions.
- You have kidney failure and are not on dialysis.
What the medicinal ingredients are in 1000 mL)
|Ingredients (g)||Travasol E||Travasol |
|L lysine hydrochloride||5.8||5.8||5.8|
|Sodium acetate |
|Dibasic potassium |
|Magnesium chloride |
What the nonmedicinal ingredients are
Glacial acetic acid (for pH adjustment), Nitrogen and Water for injection.
What dosage forms it comes in
TRAVASOL E / TRAVASOL product is a solution for infusion (into the vein). It is supplied in a bag.
The 10% amino acids solution provides a different amount of amino acids and, with some formulations, electrolytes so that your healthcare professional can tailor the infusion to your particular needs.
Warnings and Precautions
BEFORE you use TRAVASOL E (amino acids WITH electrolytes injection) or TRAVASOL (amino acids injection), talk to your healthcare professional if:
- You are allergic to any ingredients. (See What the medicinal ingredients are and What the nonmedicinal ingredients are).
- You suffer from metabolic acidosis (when the blood is excessively acid)
- You have kidney or liver problems
- You are taking any other medicines on a regular basis.
- You are pregnant or intend to become pregnant
- You are breastfeeding or intend to breastfeed
- You have pulmonary edema (collection of fluid into the lung tissue)
- You have heart failure
- You have fluid overload (too much water in your body)
In all cases, your healthcare professional will base his/her decision to treat you or your child on factors such as age, weight and clinical condition, together with the results of any tests. Always be sure to check with your healthcare professional if anything about your condition changes.
In newborns and infants, your healthcare professional will measure blood ammonia frequently to check for the presence of a congenital abnormality of amino acid metabolism.
Your healthcare professional will need to monitor how you are doing while you are on this intravenous nutritive supplement. This means that you will need to have laboratory tests done on a routine basis.
Interactions with this Medication
No drug interaction studies have been done with TRAVASOL E (amino acids WITH electrolytes injection) or TRAVASOL (amino acids injection).
TRAVASOL E / TRAVASOL product must NOT be administered simultaneously with blood through the same infusion tubing.
Let your healthcare professional know if you are receiving corticosteroids or corticotropin.
There may be interactions between the nutrients in TRAVASOL E / TRAVASOL product and one or more of your medications, for example diuretics, blood pressure drugs, or drugs used to suppress your immune system. You should review your medications with your healthcare professional.
Proper Use of this Medication
TRAVASOL E / TRAVASOL products are in pharmacy bulk package and are not for direct infusion. Your healthcare professional will reconstitute the products so they can be administered safely.
Your healthcare professional will select the best TRAVASOL E (amino acids WITH electrolytes injection) or TRAVASOL (amino acids injection) product for you, based on your age and body weight. Your healthcare professional will ensure that you are getting sufficient calories so that the amino acids from TRAVASOL E / TRAVASOL product will be absorbed. Your healthcare professional will also specify a flow rate corresponding to your needs and medical condition.
If your dose is too high or is infused too quickly, the amino acid content may make your blood too acidic. Giving too high a volume may cause fluid overload.
To prevent these events occurring, your healthcare professional will regularly monitor your condition and test your blood and urine parameters.
|In case you feel you have been administered too much TRAVASOL E / TRAVASOL product, contact your healthcare practitioner (e.g. healthcare professional), hospital emergency department or the regional poison control centre, even if there are no symptoms.|
If you feel a dose has been missed contact your attending healthcare professional.
Side Effects and what to do about them
If you notice any changes in the way you feel during or after the treatment, tell your healthcare professional or another member of your medical team immediately.
The tests your healthcare professional will perform while you are taking the intravenous nutritive supplement should reduce the risk of side effects.
If any symptoms of an allergic reaction develop, such as fever or chills, shivering, skin rashes, severe headache or breathing difficulties, contact your attending healthcare professional immediately.
Other side effects may include rapid heart beat, sweating, nausea, vomiting, abdominal swelling, pain on the right side of your belly area (liver).
If any side effect gets serious, or if you notice any side effect not listed in this leaflet, please tell your healthcare professional or a member of your medical team right away.
Occasional reddening and stinging may occur at the point where the tubing enters the body. If this occurs, tell your healthcare professional or nurse immediately.
Serious side effects, how often they happen and what to do about them
|Symptom / effect||Talk with |
|Stop the |
|In all |
This is not a complete list of side effects. For any unexpected effects while taking TRAVASOL E (amino acids WITH electrolytes injection) or TRAVASOL (amino acids injection), contact your healthcare professional.
How to Store it
The heatlhcare professional will store the TRAVASOL E / TRAVASOL product at temperatures between 15°C and 25°C, protected from light and kept from freezing.
Reporting Side Effects
You can help improve the safe use of health products for Canadians by reporting serious and unexpected side effects to Health Canada. Your report may help to identify new side effects and change the product safety information.
3 ways to report:
- Online at MedEffect;
- By calling 1-866-234-2345 (toll-free);
- By completing a Consumer Side Effect Reporting Form and sending it by:
- Fax to 1-866-678-6789 (toll-free), or
- Mail to: Canada Vigilance Program
Postal Locator 0701E
Ottawa, Ontario K1A 0K9
Postage paid labels and the Consumer Side Effect Reporting Form are available at MedEffect.
NOTE: Contact your health professional if you need information about how to manage your side effects. The Canada Vigilance Program does not provide medical advice.
This document plus the full product monograph, prepared for health professionals can be obtained by contacting the sponsor, Baxter Corporation, at 1-888-719-9955.