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Saphris® (asenapine) – Instructions For Use

Manufacture: Forest Pharmaceuticals (Allergan)
Country: Angola
Condition: Bipolar I Disorder (Bipolar Disorder), Schizophrenia
Class: Atypical antipsychotics
Form: Tablets
Suitable for: asenapine maleate, include gelatin, mannitol, sucralose, and black cherry flavo

sublingual tablets

Read these Instructions for Use before you start using SAPHRIS and each time you get a refill. There may be new information. This leaflet does not take the place of talking to your doctor about your medical condition or your treatment.


  • For sublingual (under your tongue) use only
  • Do not remove tablet until ready to administer.
  • Use dry hands when handling tablet.

Your SAPHRIS tablets

Directions for Taking your SAPHRIS Tablets:

Step 1. Firmly press and hold thumb button, then pull out the tablet pack (see Figure A). Do not push tablet through the tablet pack. Do not cut or tear the tablet pack.

Figure A

Step 2. Peel back the colored tab (see Figure B).

Figure B

Step 3. Gently remove the tablet (see Figure C). Do not split, cut or crush the tablet.

Figure C

Step 4. Place the whole tablet under tongue and allow it to dissolve completely (see Figure D).

Figure D

Do not chew or swallow the tablet.

Do not eat or drink for 10 minutes (See Figure E).

Figure E

Step 5. Slide the tablet pack back into case until it clicks (see Figure F).

Figure F

Storing SAPHRIS tablets:

Store SAPHRIS tablets at room temperature between 68 °F to 77 °F (20 °C to 25 °C).