What Metronidazole 5mg Injection is used for and how to use it
Россия
  • Россия
  • Украина

Metronidazole 5mg Injection - Consumer Medicine Information

Manufacture: Baxter
Country: Canada
Condition: Amebiasis, Aspiration Pneumonia, Bacteremia, Bacterial Infection, Bacterial Vaginitis, Balantidium coli, Bone infection (Osteomyelitis), Crohn's Disease, Maintenance, Crohn's Disease, Acute, Clostridial Infection, Deep Neck Infection, Dental Abscess, Dracunculiasis, Diverticulitis, Dientamoeba fragilis, Endocarditis, Giardiasis, Helicobacter Pylori Infection, Intraabdominal Infection, Joint Infection, Lemierre's Syndrome, Meningitis, Nongonococcal Urethritis, Pelvic Inflammatory Disease, Peritonitis, Pneumonia, Pseudomembranous Colitis, Pouchitis, Skin or Soft Tissue Infection, Surgical Prophylaxis, STD Prophylaxis, Trichomoniasis
Class: Amebicides, Miscellaneous antibiotics
Form: Liquid solution, Intravenous (IV)
Ingredients: metronidazole, citric acid, nitrogen, sodium chloride, sodium phosphate, water for injection

METRONIDAZOLE 5MG/ML INJECTION
(Metronidazole)

About this medication

What the medication is used for

Metronidazole 5mg/ml Injection is used to:

  • treat infections of the abdominal cavity, brain or lung.
  • prevent infections in patients having colorectal surgery.

What it does

Metronidazole 5mg/ml Injection kills the bacteria that cause the infection.

When it should not be used

Do not use Metronidazole 5mg/ml Injection and tell your doctor if you:

  • are allergic (hypersensitive) to metronidazole
  • are allergic (hypersensitive) to any of the nonmedicinal ingredient in the formulation (see “What the nonmedicinal ingredients are) or components of the VIAFLEX plastic container
  • have a disease of the nervous system
  • have a history of blood-disorders, hypothyroidism (underactive thyroid gland) or hypoadrenalism (underactive adrenal gland)

What the medicinal ingredient is

Metronidazole

What the nonmedicinal ingredients are

Citric Acid

Nitrogen

Sodium Chloride

Sodium Phosphate

Water for Injection

What dosage forms it comes in

Metronidazole 5mg/ml Injection, solution

Warnings and precautions

BEFORE receiving Metronidazole 5mg/ml Injection talk to your doctor, pharmacist or nurse if you:

  • have liver problems
  • have an active or chronic severe disease of the nervous system
  • have any blood disorder (e.g., transient eosinophilia, leukopenia or other)
  • have a history of edema (swelling of the legs, ankles and/or feet)
  • are pregnant or plan to get pregnant
  • are breastfeeding, or plan to breastfeed, as metronidazole is excreted in human breast milk.
  • are less than 18 years of age

Interactions with this medication

As with most medicines, interactions with other drugs are possible. Tell your doctor, nurse, or pharmacist about all the medicines you take, including drugs prescribed by other doctors, vitamins, minerals, natural supplements, or alternative medicines.

The following may interact with Metronidazole 5mg/ml Injection

  • Disulfiram
  • Medicines used to thin the blood such as warfarin (Coumadin)
  • Phenobarbital or Phenytoin (Dilantin)
  • Vecuronium
  • Lithium
  • Busulfan (Myleran)

Do not drink any alcohol while you are receiving Metronidazole 5mg/ml Injection. Consumption of alcohol with metronidazole may cause headaches and flushing.

Proper use of this medication

Usual Adult Dose

The appropriate dose is selected by the Health Care Professional and is administered through a vein.

Overdose

In case of drug overdose, contact a health care practitioner, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms.

Missed Dose

If you miss your scheduled infusion, contact your doctor or nurse as soon as possible to schedule your next treatment.

Side effects and what to do about them

Side effects may include:

  • Nausea, diarrhea, vomiting, constipation
  • Indigestion, loss of appetite
  • abdominal pain
  • dry mouth, furred tongue
  • unpleasant metallic taste
  • dark urine
  • painful urination
  • flushing
  • headaches
  • trouble sleeping, feeling
  • skin rash and itching

Metronidazole 5mg/ml Injection can cause abnormal blood test results. Your doctor will decide when to perform blood tests and will interpret the results

Serious side effects, how often theyhappen and what to do about them

Symptom / effectTalk with your doctor, nurse, or pharmacistStop taking drug and seek immediate medical help
Only if severeIn all cases
Allergic Reaction: rash, blisters, mouth sores, hives, swelling of the face, lips, tongue or throat, difficulty swallowing or breathing, fever
Chest pain, unusually rapid, strong, or irregular heartbeat.
Eye disorders: blurred vision, vision loss
Stomach pain, diarrhea which can be bloody, fever
Nervous System Disorders: inability to coordinate voluntary movements, problems using your arms and legs, feel confused, seizures, stiff neck associated with headache, dizziness, drowsiness and insomnia
Numbness, burning,tingling, pain in the hands and/or feet, sensitivity to touch
Vaginal Yeast Infection: vaginal dryness, burning and discharge
Inflammation at the needle site (thrombophlebitis): Pain, burning, swelling

This is not a complete list of side effects. For any unexpected side effects while taking Metronidazole 5mg/ml Injection, contact your doctor, nurse or pharmacist.

How to store it

Store at room temperature (15° to 25°C).

Keep out of reach and sight of children.

Reporting suspected side effects

You can report any suspected adverse reactions associated with the use of health products to the Canada Vigilance Program by one of the following 3 ways:

  • Report online at www.healthcanada.gc.ca/medeffect
  • Call toll-free at 1-866-234-2345
  • Complete a Canada Vigilance Reporting Form and:
    • Fax toll-free to 1-866-678-6789, or
    • Mail to: Canada Vigilance Program
                     Health Canada
                     Postal Locator 0701E
                     Ottawa, ON K1A 0K9

Postage paid labels, Canada Vigilance Reporting Forms and the adverse reaction reporting guidelines are available on the MedEffect™ Canada Web site at www.healthcanada.gc.ca/medeffect.

NOTE: Should you require information related to the management of side effects, contact your health professional. The Canada Vigilance Program does not provide medical advice.

More information

This document plus the full product monograph, prepared for health professionals can be obtained by contacting the sponsor, Baxter Corporation, at:

1-800-387-8399