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Metoclopramide Injection - Instructions For Use

Manufacture: Fresenius Kabi USA, LLC
Country: United States
Condition: Gastroparesis, Migraine, Nausea (Nausea/Vomiting)
Class: GI stimulants, Miscellaneous antiemetics
Form: Liquid solution, Intramuscular (IM), Intravenous (IV)
Ingredients: Metoclopramide


CAUTION: Certain glass syringes may malfunction, break or clog when connected to some Needleless Luer Access Devices (NLADs) and needles. This syringe has a larger internal syringe tip and an external collar (luer collar). The external collar must remain attached to the syringe. Data show that the syringe achieves acceptable connections with the BD Eclipse Needle and the Terumo SurGuard2 Safety Needle and with the following non-center post NLADs: Alaris SMARTSITE, B-Braun ULTRASITE, BD-Q SYTE, Maximum MAX PLUS, and B -Braun SAFSITE. The data also show acceptable connections are achieved to the center post ICU Medical CLAVE. However, spontaneous disconnection of this glass syringe from needles and NLADs with leakage of drug product may occur. Assure that the needle or NLAD is securely attached before beginning the injection. Visually inspect the glass syringe -needle or glass syringe–NLAD connection before and during drug administration. Do not remove the clear plastic wrap around the external collar. (See Figure 1)

Figure 1

  1. Inspect the outer packaging (blister pack) by verifying:
    • blister integrity
    • drug name
    • drug strength
    • dose volume
    • route of administration
    • expiration date to be sure that the drug has not expired
    • sterile field applicability
      Do not use if package has been damaged.
  2. Peel open the paper (top web) of the outer packaging that displays the product information to access the syringe. Do not pop syringe through.
  3. Bend the plastic part of the outer packaging (thermoform) so as to present the plunger rod for syringe removal. (See Figure 2)
    Figure 2

  4. Perform visual inspection on the syringe by verifying:
    • absence of syringe damage
    • absence of external particles
    • absence of internal particles
    • proper drug color
    • expiration date to be sure that the drug has not expired
    • drug name
    • drug strength
    • dose volume
    • route of administration
    • integrity of the plastic wrap around the external collar
  5. Do not remove plastic wrap around the external collar. Push plunger rod slightly to break the stopper loose while tip cap is still on.
  6. Do not remove plastic wrap around the external collar. Remove tip cap by twisting it off. (See Figure 3)
    Figure 3

  7. Discard the tip cap.
  8. Expel air bubble.
  9. To use the syringe in pediatric patients or patients who need a dose less than 10 mg, adjust dose into sterile material.
  10. Connect the syringe to appropriate injection connection depending on route of administration. Before injection, ensure that the syringe is securely attached to the needle or needleless luer access device (NLAD).
  11. Depress plunger rod to deliver medication. Ensure that pressure is maintained on the plunger rod during the entire administration.
  12. Remove syringe from NLAD (if applicable) and discard into appropriate receptacle. If delivering medication with a needle, to prevent needle stick injuries, do not recap needle.