What Docetaxel is used for and how to use it
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Docetaxel - Consumer Medicine Information

Manufacture: Dr. Reddy's Laboratories, Inc.
Country: India
Condition: Breast Cancer, Breast Cancer, Metastatic, Non-Small Cell Lung Cancer, Prostate Cancer
Class: Mitotic inhibitors
Form: Liquid solution, Intravenous (IV)
Ingredients: docetaxel, dehydrated alcohol,citric acid, polysorbate 80

Intravenous Infusion

What is the Most Important Information I Should Know About Docetaxel Injection Docetaxel Injection can Cause Serious Side Effects, Including Death

1. The chance of death in people who receive docetaxel injection is higher if you:

  • have liver problems
  • receive high doses of docetaxel injection
  • have non-small cell lung cancer and have been treated with chemotherapy medicines that contain platinum

2. Docetaxel injection can affect your blood cells .

Your doctor should do routine blood tests during treatment with docetaxel injection. This will include regular checks of your white blood cell counts. If your white blood cells are too low, your doctor may not treat you with docetaxel injection until you have enough white blood cells. People with low white blood counts can develop life- threatening infections. The earliest sign of infection may be fever. Follow your doctor’s instructions for how often to take your temperature while taking docetaxel injection. Call your doctor right away if you have a fever.

3. Serious allergic reactions can happen in people who take docetaxel injection.Serious allergic reactions are medical emergencies that can lead to death and must be treated right away.

Tell your doctor right away if you have any of these signs of a serious allergic reaction:

  • trouble breathing
  • sudden swelling of your face, lips, tongue, throat, or trouble swallowing
  • hives (raised bumps), rash, or redness all over your body

4. Your body may hold too much fluid (severe fluid retention) during treatment with docetaxel injection.

This can be life threatening. To decrease the chance of this happening, you must take another medicine, a corticosteroid, before each docetaxel injection treatment. You must take the corticosteroid exactly as your doctor tells you. Tell your doctor or nurse before your docetaxel injection treatment if you forget to take the corticosteroid dose or do not take it as your doctor tells you.

What is Docetaxel Injection

Docetaxel injection is a prescription anti-cancer medicine used to treat certain people with:

  • breast cancer
  • non-small cell lung cancer
  • prostate cancer
  • stomach cancer
  • head and neck cancer

It is not known if docetaxel injection is effective in children.

Who Should not Receive Docetaxel Injection

Do not receive docetaxel injection if you:

  • have had a severe allergic reaction to:
  • docetaxel, the active ingredient in docetaxel injection, or
  • any other medicines that contain polysorbate 80. Ask your doctor or pharmacist if you are not sure. See “What is the most important information I should know about docetaxel injection?” for the signs and symptoms of a severe allergic reaction. have a low white blood cell count.

What Should I Tell My Doctor Before Receiving Docetaxel Injection

Before you receive docetaxel injection, tell your doctor if you:

  • are allergic to any medicines. See “Who should not receive docetaxel injection?” Also, see the end of this leaflet for a complete list of the ingredients in docetaxel injection.
  • have liver problems
  • have any other medical conditions
  • are pregnant or plan to become pregnant. Docetaxel injection can harm your unborn baby.
  • are breastfeeding or plan to breastfeed. It is not known if docetaxel passes into your breast milk. You and your doctor should decide if you will receive docetaxel injection or breastfeed.

Tell your doctor about all the medicines you take including prescription and over -the-counter medicines, vitamins, and herbal supplements. Docetaxel injection may affect the way other medicines work, and other medicines may affect the way docetaxel injection works.Know the medicines you take. Keep a list of them to show it to your doctor and pharmacist when you get a new medicine.

How Will I Receive Docetaxel Injection

  • Docetaxel injection will be given to you as an intravenous (IV) injection into your vein, usually over 1 hour.
  • Docetaxel injection is usually given every 3 weeks.
  • Your doctor will decide how long you will receive treatment with docetaxel injection.
  • Your doctor will check your blood cell counts and other blood tests during your treatment with docetaxel injection to check for side effects of docetaxel injection.
  • Your doctor may stop your treatment, change the timing of your treatment, or change the dose of your treatment if you have certain side effects while receiving docetaxel injection.

What are the Possible Side Effects of Docetaxel Injection

Docetaxel injection may cause serious side effects including death.

  • See “What is the most important information I should know about docetaxel injection?”
  • Acute Myeloid Leukemia (AML), a type of blood cancer, can happen in people who take docetaxel injection along with certain other medicines. Tell your doctor about all the medicines you take.
  • Other Blood Disorders . Changes in blood counts due to leukemia and other blood disorders may occur years after treatment with docetaxel injection.
  • Skin Reactions including redness and swelling of your arms and legs with peeling of your skin. Neurologic Symptoms including numbness, tingling, or burning in your hands and feet.
  • Vision Problems including blurred vision or loss of vision
  • Docetaxel Injection contains alcohol. The alcohol content in docetaxel injection may impair your ability to drive or use machinery right after receiving docetaxel injection. Consider whether you should drive, operate machinery or do other dangerous activities right after you receive docetaxel injection treatment.

The most common side effects of docetaxel injection include:

  • changes in your sense of taste
  • feeling short of breathconstipation
  • decreased appetite
  • changes in your fingernails or toenails
  • swelling of your hands, face or feet
  • feeling weak or tired
  • joint and muscle pain
  • nausea and vomiting
  • diarrhea
  • mouth or lips sores
  • hair loss
  • rash
  • redness of the eye, excess tearing
  • skin reactions at the site of docetaxel injection administration such as increased skin pigmentation, redness, tenderness, swelling, warmth or dryness of the skin.
  • tissue damage if docetaxel injection leaks out of the vein into the tissues

Tell your doctor if you have any side effect that bothers you or does not go away. These are not all the possible side effects of docetaxel injection. For more information ask your doctor or pharmacist.

Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

General Information About Docetaxel Injection

Medicines are sometimes prescribed for purposes other than those listed in a Patient Information leaflet. This Patient Information leaflet summarizes the most important information about docetaxel injection. If you would like more information, talk with your doctor. You can ask your pharmacist or doctor for information about docetaxel injection that is written for health professionals.

For more information contact 1-888-375-3784

What are the Ingredients in Docetaxel Injection

Active ingredient: docetaxel

Inactive ingredients include: dehydrated alcohol,citric acid and polysorbate 80

Every three-week injection of docetaxel injection for breast, non-small cell lung and stomach, and head and neck cancers

Take your oral corticosteroid medicine as your doctor tells you.