BSS Irrigating Solution: Indications, Dosage, Precautions, Adverse Effects
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BSS Irrigating Solution - Product Information

Manufacture: Alcon
Country: United States
Condition: Surgical Prophylaxis
Class: Ophthalmic lubricants and irrigations
Form: Liquid solution
Ingredients: Sodium chloride, Potassium chloride, Calcium chloride dihydrate, Magnesium chloride hexahydrate, Sodium acetate trihydrate, Sodium citrate dihydrate, Sodium hydroxide and/or hydrochloric acid and Water for injection

Sterile Irrigating Solution

(balanced salt solution)


BSS Sterile Irrigating Solution is a sterile balanced salt solution, each mL containing sodium chloride (NaCl) 0.64%, potassium chloride (KCl) 0.075%, calcium chloride dihydrate (CaCl2•2H2O) 0.048%, magnesium chloride hexahydrate (MgCl2•6H2O) 0.03%, sodium acetate trihydrate (C2H3NaO2•3H2O) 0.39%, sodium citrate dihydrate (C6H5Na3O7•2H2O) 0.17%, sodium hydroxide and/or hydrochloric acid (to adjust pH),

and water for injection. The pH is approximately 7.5. The osmolality is approximately 300 mOsm/Kg.

Clinical Pharmacology

BSS Sterile Irrigating Solution is an isotonic solution for use in irrigating tissues of the eyes.

Indications and Usage

For use as an extraocular and intraocular irrigating solution during ocular surgical procedure involving perfusion of the eye with an expected maximum duration of less than 60 minutes.


  • Do not use unless outer overwrap is intact, product is clear, seal is intact and bag is undamaged.
  • Do not use if product is discolored or contains a precipitate.
  • SINGLE patient use only. The contents of this bag should not be used in more than one patient.
  • This solution contains no preservative, unused contents should be discarded.


Open under aseptic conditions only.

Studies suggest that intraocular irrigating solutions which are iso-osmotic with normal aqueous fluids should be used with caution in diabetic patients undergoing vitrectomy since intraoperative lens changes have been observed.

There have been reports of corneal clouding and edema following ocular surgery in which BSS Sterile Irrigating Solution was used as an irrigating solution.

Adverse Reactions

Irrigation or any other trauma may result in corneal swelling or bullous keratopathy.

Post-operative inflammatory reactions as well as incidents of corneal edema and corneal decompensation have been reported.

Dosage and Administration

This irrigating solution should be used according to standard format for each surgical procedure. Follow directions of the particular administration set to be used. Remove the outer overwrap. Clean and disinfect the rubber stopper by using a sterile alcohol wipe. Insert the spike aseptically into the bag through the target area of the rubber stopper. Allow the fluid to flow and remove air from the tubing before irrigation begins.

How Supplied

BSS Sterile Irrigating Solution is supplied in a clear polypropylene bag using a grey butyl stopper and aluminum seal packaged in a clear, multilayered plastic outer overwrap.

500 mL in a bag: NDC 0065-1795-04.


Store at 36° - 77°F (2° - 25°C).