What Biltricide is used for and how to use it
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Biltricide - Consumer Medicine Information

Manufacture: Bayer
Country: Canada
Condition: Cysticercus cellulosae, Dog Tapeworm (Dipylidium caninum), Echinococcus, Fasciolopsis buski, Intestinal Fluke, Fish Tapeworm Infection (Diphyllobothrium latum), Heterophyes heterophyes, Intestinal Fluke, Hymenolepis nana, Dwarf Tapeworm, Liver Fluke (Clornorchis sinensis), Metagonimus yokogawai, Intestinal Fluke, Naophyetus salmincola, Opisthorchis viverrini, Liver Fluke, Paragonimus westermani, Lung Fluke, Schistosoma haematobium, Schistosoma japonicum, Schistosoma mansoni, Schistosoma mekongi, Taenia saginata, beef tapeworm, Taenia solium, pork tapeworm
Class: Anthelmintics
Form: Tablets
Ingredients: praziquantel, corn starch, magnesium stearate, microcrystalline cellulose, polyvidone 25, sodium lauryl sulphate, polyethylene glycol 4000, methylhydroxypropyl-cellulose, titanium dioxide

(Praziquantel) Tablets

About this medication

What the medication is used for

BILTRICIDE (praziquantel) can only be obtained with a prescription from your doctor. This drug has been prescribed by your doctor to treat the infection you have that is caused by worms and/or liver flukes. Do not give this medicine to other people.

What it does

BILTRICIDE interferes with the action of the cell membrane, leading to parasite death and reduction of the infection.

When it should not be used

Do not use BILTRICIDE if you:

  • took it before and had an allergic reaction to it (see “What the nonmedicinal ingredients are”)
  • have a parasitic worm infection of the eye (ocular cysticercosis)
  • are taking rifampin at the same time because the amount of BILTRICIDE in your body may be lowered below the level required to treat your infection.

What the medicinal ingredient is


What the nonmedicinal ingredients are

Corn starch, Magnesium stearate, Microcrystalline cellulose, Polyvidone 25, Sodium lauryl sulphate, Polyethylene glycol 4000, Methylhydroxypropyl-cellulose, Titanium dioxide

What dosage forms it comes in

BILTRICIDE is supplied as a 600 mg white, oblong tablet with three notches. It is marked BAYER on one side and LG on the other. When broken, each of the four pieces that result contains 150 mg of active ingredient (praziquantel). This allows your doctor to easily adjust the dose depending on your weight.

Pieces are broken off by pressing the notch with your thumbnails. If only one quarter of a tablet is required, this is best achieved by breaking the tablet from the outer end.

Warnings and precautions

Tell your doctor about all the medications you are taking, including prescription, non-prescription drugs and natural health products.

BEFORE you use BILTRICIDE talk to your doctor or pharmacist if you have or have had any of the following conditions:

  • you are pregnant or planning to become pregnant
  • you are breastfeeding or planning to breastfeed. BILTRICIDE is excreted in human breast milk. Discuss with you doctor if breastfeeding is right for your infant.
  • you have a history of epilepsy
  • you have problems with your kidney or liver function
  • you have problems with your heart

The safety and effectiveness of BILTRICIDE in children under 4 years of age has not been established.

You should not drive or operate machinery on the day of your treatment and during the next 24 hours as your reflexes may be impaired.

Interactions with this medication

Talk to your doctor before using any of the following drugs which may interact with BILTRICIDE. Your doctor may suggest alternate medications or a change in dosage:

  • Albendazole
  • Anticonvulsants (phenytoin, fosphenytoin, carbamazepine and phenobarbital)
  • Anti-fungal agents (miconazole, ketoconazole)
  • Cimetidine
  • Chloroquine
  • Dexamethasone

Glucose and bicarbonate can cause a decrease in BILTRICIDE levels in your blood.

Avoid eating grapefruit or drinking grapefruit juice while you are using this medicine.

Tell your doctor or pharmacist if you are taking or have recently taken any other medication, including medications obtained without a prescription as well as vitamins and herbal supplements, such as St. John’s Wort (Hypericum perforatum).

Proper use of this medication

Usual dose

The dose depends on your weight. You must take the medicine exactly as it is prescribed by your doctor, as a one day treatment. If you are not sure how many tablets to take or how often to take them, consult your doctor or pharmacist.

You should not change the dose prescribed by your doctor.

The tablets should be swallowed whole with some liquid, preferably during or after meals. Keeping the tablets (and pieces of the tablets) in your mouth may release a bitter taste which can cause you to gag or vomit.

The time between doses should be at least 4 hours and not more than 6 hours.


In case of drug overdose, contact your healthcare professional, hospital emergency department or regional poison control centre, even if there are no symptoms.

Side effects and what to do about them

After taking your medicine you may experience some side effects. These vary according to the dose and duration of your treatment. They also depend on the type of infection you have, how long you have had the infection, and where in your body the infection is. The side effects, if there are any, are most often one or more of the following:

  • abdominal pain
  • dizziness
  • drowsiness
  • diarrhea
  • fever
  • headache
  • hives (urticaria)
  • loss of appetite
  • muscle pain
  • nausea
  • rash
  • tiredness
  • vomiting
  • weakness

Often it is hard to tell if the side effects are due to the medicine or the infection itself. If you are concerned about how you are feeling after you take the medicine, or if you feel noticeably worse, contact your doctor or pharmacist as soon as possible.

Serious side effects, how often they happen and what to do about them

FrequencySymptom/ EffectTalk with your doctor or pharmacistStop taking drug and call your doctor or pharmacist
Only if severeIn all cases
Very RareAllergic Reaction: rash, hives, swelling of the face, lips, tongue or throat, difficulty swallowing or breathing,
Irregular or rapid heartbeat
Bloody diarrhea

This is not a complete list of side effects. For any unexpected effects while taking BILTRICIDE, contact your doctor or pharmacist. 

How to store it

Store this medicine at room temperature below 30°C. Keep this and all medicine in a safe place out of the reach and sight of children. Do not store in a damp place and keep away from light.

Reporting suspected side effects

You can report any suspected adverse reactions associated with the use of health products to the Canada Vigilance Program by one of the following 3 ways:

  • Report online at www.healthcanada.gc.ca/medeffect
  • Call toll-free at 1-866-234-2345
  • Complete a Canada Vigilance Reporting Form and:
    • Fax toll-free to 1-866-678-6789, or
    • Mail to: Canada Vigilance Program
                     Health Canada
                     Postal Locator 0701E
                     Ottawa, ON K1A 0K9

    Postage paid labels, Canada Vigilance Reporting Forms and the adverse reaction reporting guidelines are available on the MedEffect™ Canada Web site at www.healthcanada.gc.ca/medeffect.

NOTE: Should you require information related to the management of side effects, contact your health professional. The Canada Vigilance Program does not provide medical advice.

More information

For more information, please contact your health professional or pharmacist first, or Bayer Medical Information at 1-800-265-7382 or

This document plus the full Product Monograph, prepared for health professionals can be found at: http://www.bayer.ca or by contacting the manufacturer at the above-mentioned phone number and e-mail address.