Acuvail – Consumer Medicine Information
|Condition:||Allergic Conjunctivitis (Conjunctivitis, Allergic), Postoperative Ocular Inflammation|
|Class:||Analgesics, Ophthalmic anti-inflammatory agents|
|Form:||Eye drops (ophthalmic)|
|Ingredients:||ketorolac tromethamine, carboxymethylcellulose sodium, sodium citrate, sodium chloride; purified water with hydrochloric acid and/or sodium hydroxide to adjust pH|
ketorolac tromethamine ophthalmic solution 0.45% w/v
What the medication is used for:
ACUVAIL™ is used for treatment of pain and inflammation (swelling and redness) following cataract eye surgery.
What it does:
ACUVAIL™ (ketorolac tromethamine) is a non-steroidal anti- inflammatory drug (NSAIDs). It works by reducing the production of certain substances (such as prostaglandins) that cause inflammation, and pain.
When it should not be used:
ACUVAIL™ should not be used if you are allergic (hypersensitive) to ketorolac tromethamine or any of the other ingredients listed below or to other nonsteroidal antiiflammatory medicines such as acetylsalicylic acid, difusinal, fenoprofen, flurbiprofen, ketoprofen, indomethacin, mefanaimc acid, piroxicam, sulindac, tiaprofenic acid or tolmetin.
What the medicinal ingredient is:
What the important nonmedicinal ingredients are:
Other nonmedicinal ingredients in the product include: carboxymethylcellulose sodium, sodium citrate, sodium chloride; purified water with hydrochloric acid and/or sodium hydroxide to adjust pH.
What dosage forms it comes in:
ACUVAIL™ is a sterile solution packaged in 0.4 mL single-use plastic vials.
Warnings and precautions
BEFORE you use ACUVAIL™ talk to your doctor or pharmacist if:
- you have any allergies to ACUVAIL™ or any of its ingredients (see What the important nonmedicinal ingredients are)
- you bruise easily, or if you have bleeding problems, or if you are taking blood thinning medication
- you are allergic to acetylsalicylic acid or to any of the other non-steroidal anti-inflammatory drugs (NSAIDs)
- you wear contact lenses
- you are pregnant or intend to become pregnant
- you are breast-feeding or intend to breast-feed
- you drive or use heavy machinery. You may find that your vision is blurred for a time just after you use ACUVAIL™
WHILE taking ACUVAIL™ talk to your doctor if:
- you are not getting relief, your symptoms worsen or new eye problems develop.
Do not use Acuvail more that two weeks unless advised by your doctor. There is risk of corneal problems if ophthalmic non- steroidal anti-inflammatory drugs such as Acuvail are used beyond 14 days after the surgery.
Interactions with this medication
If you are allergic to acetylsalicylic acid or to any of the other non-steroidal anti-inflammatory drugs (e.g. diclofenac, diflunisal, fenoprofen, flurbiprofen, ibuprofen, indomethacin, ketoprofen, mefenamic acid, piroxicam, sulindac, tiaprofenic acid, tolmetin) used to treat arthritis or other muscle and joint conditions, discuss with your doctor before using ACUVAIL™.
Talk with your doctor or pharmacist if you are taking any blood thinning medication.
Tell your doctor or pharmacist if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine, vitamins, herbals products.
Proper use of this medication
Usual adult dose (18 years of age and older):
One day before your cataract surgery, apply one drop of Acuvail™ to the affected eye twice daily. Continue to apply one drop to the affected eye twice daily on the day of cataract surgery and for as long as your doctor told you. This maybe up to two weeks after cataract surgery.
Dosing on the day of cataract surgery by medical personnel Two hours before surgery, one drop is to be administered approximately every twenty minutes by medical personnel for a total of three drops. Before discharge one additional drop is to be applied.
Use the medication in the single-use vial immediately after opening and discard the remaining product immediately after use. Do not allow the tip of the vial to touch the eyes or eyes lids, eyelashes, fingers, counter surface or anything else. Contact with any surface can contaminate the product which may infect your eyes later on.
How to Use:
- Wash your hands well with soap and water before you start.
- Tilt your head back or lie down.
- Gently pull down the lower eyelid to create a small “pocket” between the eyelid and your eye. The drop will go in here.
- Do not touch your eye or eyelid, surrounding areas or other surfaces with the tip of the unit-dose vial.
- Hold the unit-dose vial, tip pointing down, While looking up, gently squeeze the vial to release one drop into each eye that needs treatment.
- Let go of the lower lid, and close your eye for 30 seconds, longer is better (up do 5 minutes). Try not to blink or squeeze your eyelids.
- Discard the remaining content immediately after administration.
If you are using more than 1 eye drop medication, wait 5 minutes before applying the other eye drop.
ACUVAIL should not be administered while wearing contact lenses. If contact lens use is determined safe by your doctor, they should be removed before you instill the drops and may be re- inserted 15 minutes following administration.
If accidentally ingested, drink fluids to dilute and contact your local poison centre or doctor.
|In case of drug overdose, contact a health care practitioner, hospital emergency department or regional Poison Control Centre immediately, even if there are no symptoms.|
If a dose of this medication has been missed, it should be taken as soon as possible. However, if it is almost time for the next dose, skip the missed dose and go back to the regular dosing schedule. Do not double doses.
Side effects and what to do about them
The most common side effects with treatment of ACUVAIL™ include eye pain, abnormal sensation in the eye, increased fluid pressure inside the eye(s), and pupil disorder.
Acuvail may blur your vision after you instil the drops. Do not drive or perform hazardous task until you can see clearly again.
Acuvail eye drop may slow or delay healing of the eyes.
This is not a complete list of side effects. For any unexpected effects while taking ACUVAIL™, contact your doctor or pharmacist.
How to store it
Store at room temperature (15 - 30°C). Protect from light.